Một số đặc điểm lâm sàng, cận lâm sàng bệnh nhân ung thư trực tràng giai đoạn tiến triển điều trị liệu pháp tân bổ trợ toàn phần tại Bệnh viện K

To describe the clinical and paraclinical characteristics of patients with advanced-stage rectal cancer undergoing total neoadjuvant therapy at National Cancer Hospital. Subjects and Methods: A descriptive study was conducted on 33 patients from October 2022 to June 2024 at National Cancer Hospital. Results: The mean age was 58,36 years, with a male-to-female ratio of 2,67:1. The majority of patients presented with bowel dysfunction symptoms, accounting for 87,9%. On endoscopy, exophytic tumors were observed in 51,5% of cases, with the most common tumor location being the mid-rectum, observed in 63,6% of patients. MRI staging of the pelvis revealed that 81,8% of patients were in stage cT3, and 84,9% were in stage cN+. The mean pre-treatment CEA level was 6,45 ng/ml. The majority of patients were in stage III before treatment, comprising 84,8% of cases. Conclusion: The study highlights specific characteristics regarding age, gender, tumor imaging on endoscopy and MRI, and pre-treatment staging in a group of rectal cancer patients undergoing total neoadjuvant therapy at National Cancer Hospital.