Bước đầu khảo sát hoạt tính một số yếu tố đông máu và kháng đông sinh lý trên người khỏe mạnh bình thường tại bệnh viện Chợ Rẫy

Objective: Study of the activity some coagulant and anticoagulant factors in adult healthy peoples. Subjects: Adult healthy peoples, agreed to participate in research. Method: cross-sectional descriptive method. Results: There are 55 cases, and have results: - The median value of clotting factors: factor VIII: 104.1 + or - 43.2 percent, factor IX: 114.3 + or - 33.1 percent, factor XI: 108.1 + or - 27.0 percent, a2-antiplasmin: 92.8 + or - 12.5 percent; Fibrinogen: 2.7 + or - 0.4g/L, PAI-1: 0.2 - 0.7; D-dimer: 113.4 - 177.7ng/ml. - The median value of anticoagulation factors: PC: 93.8 + or - 2.3 percent, PS: 99.2 + or -10.9 percent; ATIII: 89.5 + or - 8.9 percent; APCR - V: 2.0 + or - 0.2. - The rate of increase hypercoagulability factors: mainly factor IX and factor XI. - The rate of reduction of anticoagulant factors: mainly PC and ATIII. Conclusion: The median value of coagulant and anticoagulant factors is similar to studies. While increased the hypercoagulant factors are mainly factors IX, XI and decreased anticoagulant factors are mainly protein C, antiThrombin III.