Chế tạo vật liệu tương đương trung bì từ tế bào gốc trung mô màng dây rốn trong điều kiện nuôi cấy không giá đỡ để điều trị vết thương vết bỏng

The dermal equivalent is an in vitro model of the dermal layer of skin. It is constructed by seeding dermal fibroblasts into degradable or polymeric scaffold. It can be used for wound care to accelerate wound healing process. Due to high cost and lack of dermic components, the dermal equivalent has not been used popularly. In this study, the authors developed a new dermal equivalent by seeding cord lining mesenchymal stem cells in plastic culture substrate and maintaining in specific medium to stimulate cells to secrete extracellular matrix. The morphology of dermal equivalent was investigated, and also made evaluation in animal wound model.