Đặc điểm lâm sàng, cận lâm sàng bệnh viêm màng não mủ ở người lớn tại Bệnh viện tỉnh Thanh Hóa

To contribute to improving the results of treatment and prevention of bacterial meningitis (BM) in Thanh Hoa province, a retrospective study in the period 7/2019 - 6/2022 was conducted. 24 BM adult patients responded clinical and microbiological criteria, treated at Thanh Hoa Provincial General Hospital were selected for analysis. The results showed that, in Thanh Hoa, BM occurred all year round, increasing in hot months. The disease was found in all age groups, mainly in the 41-60 age group (50.0%), 75% males, 66.7% farming occupation, and 62.5% patients with underlying disease. Clinical manifestations and cerebrospinal fluid were atypical. While fever was only seen in 87.5% of patients, symptoms such as headache, neck stiffness, vomiting, and Kernig ranged from 54.2% to 100%. The rate of BM associated with bacteremia was 62.5%. Pathogenic bacteria, including S. suis (70.8%) and S. pneumoniae (20.8%) were susceptible to third-generation cephalosporins and vancomycin, while E. coli (4.2%) and S. mitis (4.2%) resistant to these antibiotics. S. suis was common in immunocompromised patients, S. pneumoniae was associated with the route of entry.