Đánh giá hiệu quả hoá xạ trị đồng thời triệt căn ung thư hạ họng – thanh quản giai đoạn III, IVA-B với cisplatin chu kì 3 tuần

Evaluation of response to combined chemotherapy and radiation therapy with cisplatin with a 3-week cycle for stage III, IVA-B hypopharyngeal – laryngeal cancer and the relationship with clinical and subclinical characteristics. Subjects and methods: A retrospective and prospective cross-sectional descriptive study on 32 patients with laryngeal cancer III, IVA-B who were initially treated with chemoradiotherapy and cisplatin with a 3-week cycle at the Department of Physics, radiation therapy - Military Medical Hospital 103 and the Department of Radiotherapy and Radiosurgery - 108 Central Military Hospital from January 2020 to October 2022. Results: treatment response rate is high, 46.9% of clinical symptoms are gone; 56.3% responded completely; complete response in tumor was 62.5%, complete response in lymph node was 56.3%. The factors related to treatment response include: stage, general condition, enough chemotherapy, receiving enough radiation dose. Conclusion: concurrent chemoradiotherapy with cisplatin for a 3-week cycle showed effective treatment for cancer of the pharynx - larynx stage III, IVA-B.