Objectives: Evaluation a change of entropy index in target controlled infusion (TCI) anesthesia. Methods: An advanced study, clinical trial and random experiment on 60 patients who have undergone general anesthesia for operation at Viet Tiep friendship hospital in Hai Phong from January 2015 to April 2015. Results: 1. About general features: the average ages of patients from 49,48 +/- 12,55 years old, the average weight 55,02 +/- 9,09 and the average height 153,10 +/- 11,08. 2. The midvalue changes of Ce, RE and SE at the periods of 3 anesthesia grades A, B, C of Martorano: * The increasingly chloroform concentration. (Ce = 0,97 +/- 0,23jJg/ml), so the brain static charge index has a trend of decreasing RE = 70,15 +/- 5,11 and SE = 65,35 +/- 3,77 (at T2). The endotracheal laying time isto excite u1th the strongest intensity. The highest Ce-propofol (3,73 +/- 0,64 ug/ml) correspondance with RE = 38,18 +/- 6,19 and SE = 37,54 +/- 5,15 is the lowest in 12 study periods. The value of RE, SE increases correspondance with the decrease of chloroform concentration. The difference RE - SE is the largest at recuperation level and lowest at the anaesthetic level-surgery.3.The hemodynamic changes in anesthesia have no statistics sense, there are no cases of hemodynamic changes in anesthesia over 20 percent comparision with the beginning. 4. The instant endotracheal extracted time:The majority of patients extracted the instant endotracheal pipe after finishing the operation about 15 minutes (86,67 percent). There are not any patients being complications after the surgery. Conclusions: The Propofol target controlled infusion (TCI) with the ENTROPY index and the stable hemodynamic index during the operation process. This method help to rapidly wake up, early instant endotracheal extract, less side-effects. This is the safe and effective anaesthetic method for the operation.
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