Objective:: To evaluate the rate of HCV-RNA in hemodialysis patients with anti-HCV positive in Bach Mai hospital as well as HCV genotypes in these patients. Subject: The study was conducted on 70 hemodialysis patients with anti-HCV (+) at Bach Mai Hospital for 2 years (2006-2008). Methods: The study was conducted by the description of cross-sectional. The presence of HCV-RNA in patients with anti-HCV positive was determined by real time RT PCR with qualitative COBA AmpliPrep/ COBA TaqMan HCV Test. (Roche) and HCV genotype was determined by real time Rl PCR. Results and conclusion: Of the 70 hemodialysis patient, 64 (91.43 percent) were found to be HCVRNA positive. Among them, 36 (56.25 percent) had viral load more than 106 copy/ml, showed risk of patient-to-patient transfer of HCV infection in hemodialysis unit. The distribution of the HCV genotype was as follows: HCV genotype 6 (50 percent) was the most prevalence, followed by genotype 1 (43.75 percent); and 4 patients were observed as with mixed genotype infection: associating genotypes 1 and 2 (1. 56 percent); associating genotypes 2 and 6 (4.69 percent).
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