Khảo sát tính nhạy cảm kháng sinh và tỷ lệ mang gene độc lực scpB và lmb của các chủng Streptococcus agalactiae phân lập từ phụ nữ mang thai đến khám tại bệnh viện Trường Đại học Y Dược Huế

Data on the antimicrobial susceptibility profiles and the frequency of the scpB and lmb virulence genes among Streptococcus agalactiae (GBS) f-rom pregnant women could develop a strategic for preventing neonatal GBS infections. This study was aimed (1) To determine the antibiotic susceptibility of GBS strains isolated f-rom the pregnant women; and (2) To determine the scpB and lmb virulence genes among isolated GBS strains. Materials and method 24 GBS strains were subjected to the antibiotic susceptibility testing (AST) by the disc diffusion (Kirby-Bauer) method. The virulence genes (scpB and lmb) were detected by using PCR method. Results All 24 GBS were susceptible to penicillin, cefotaxime, vancomycin and clindamycin. A large proportion of GBS isolates were found to be resistant to erythromycin (75%) and tetracycline (66.7%). The resistance rates for levofloxacin and chloramphenicol were 54.2% and 20.8%, respectively. The scpB gene was present in 95.8% of these GBS isolates and the lmb in 91.7% of isolates.