Nghiên cứu ảnh hưởng của chế phẩm Mecook đối với chức năng và hình thái gan và thận trên động vật thực nghiệm

The product of Mecook was used to evaluate the function and morphology of rabbits' liver and kidney. Research results showed trlat after 4 weeks of continuous oral using dose of 0.12 g/kg/day (equivalent of clinical dose) and 1.2g/kg/day (10 times of clinical dose), there was no recorded changes on the results of liver function tests (ALT, AST, total bilirubin, protein) and renal function (urea, creatinine). Normal liver cells and no degradation were seen in the liver micro-structure of the treatment group; however, some rabbits had mild kidney damage. This nonspecific lesion was also recorded the control group.