Nghiên cứu biến đổi số lượng và hình thái mẫu tiểu cầu ở bệnh nhân giảm tiểu cầu chảy máu ngoại vi

Thrombocytopenia is commonly encountered in haematological and non-haematologlcal disorders. Bone marrow aspiration plays. a major role in diaqnosis. Objective: to analyse the chanqes in number and morphology of the megakaryocytes in patient with Thrombocytopenia. Patients and methods: This restrospective and prospective cross. sectional study was carried out at 108 military central hospital. Results: 400 cases with thrombocytopenia. Mean age of patients was 53,2 years. Maximum number of cases was seen in age group of above 45 years. Idiopathic thrombocytopenic purpura (ITP) was the commonest cause followed by hypoplastic marrow, acute leukaemia respectively. Most patients increased number of megacaryocyte with immature form is ITP. Conclusion: bone marrow aspiration is an important diagnostic modality to determine the aetiology of thrombocytopenia.