Nghiên cứu chọc hút dịch ối chẩn đoán thai nhi nhiễm virus Rubella bằng kỹ thuật PCR - Realtime tại bệnh viện Phụ sản Trung ương

Objective: To compare the results of amniocentesis with the results of biochemical test from cordocentesis to diagnose rubella infection, assess the sensitivity and specificity of PCR-Real time. Methods: this is a cross-sectional description in pregnant women infected with rubella in 6-18 weeks gestation and voluntarily participate in the study. Results: All cases of diagnostic amnioscentesis fetal rubella virus infection by PCR-Real time resuls are highly acurate compared with the results biochemical test immune fetal cord blood. The sensitivity of the PCR-Real time method amniocentesis resuls as high as 96,6 percent, specificity 100 percent, accuracy of amniotic fluid PCR testing umbilical cord blood 19M was 98,4 percent. Conclusion: The results poked of amniocentesis by PCR-Real time sensitivity, specificity and acuracy. Recommendation: Should be applied PCR-Real time amniotic fluid tests for fetal diagnosis of rubella infection for all pregnant women infected with rubella.