Nghiên cứu đặc điểm lâm sàng và cận lâm sàng của bệnh nhân bạch cầu tủy cấp tại khoa Huyết học lâm sàng, Bệnh viện Trung ương Quân đội 108

Background: acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cell characterized by the rapid growth of abnormal white blood cell in the bone marrow and interfere with the production of normal blood cell. Objective: describe the clinical and paraclinical characteristics in AML patients treated at Department of Haematological Diseases of No.108 Military Central Hospital. Patients and Methods: A restrospective cross sectional study on 30 AML patients from 2008 to 2013. Results: Mean age of patients was 52,27 + or - 15,67 years (20-88); the ratio of females to males was 1:1; 46,7 percent of patients had fever, 93,3 percent had anemia, 46,7 percent had skin and mucosal bleeding. Classification of (AML) by FAB: M2 was 33,3 percent, M1 - 23,3 percent, M4 -16,7 percent, M0 - 10 percent, M3 - 6,7 percent, M6 - 6,7 percent va M5 - 3,3 percent. Median value of peripheral blood and bone marrow were: WBC 44,89 + or - 50,79 G/L; Neutrophil 11,14 + or - 16,61 G/L; HGB 85,73 + or - 17,96 G/L; PLT 96,39 + or - 94,25 G/L; number of bonne marrow cells 180,18 + or - 112,20 G/L, number of myeloblast in bone marrow 70,8 + or - 19,9 percent; myeloblast in peripheral blood 52,3 + or - 29,68 percent. Conclusion: increase in the percentage of myeloblast in peripheral blood and in bone marrow, anemia, hemorrhage and infection are the main criteria for the diagnosis of AML.