Nghiên cứu độc tính cấp và ảnh hưởng của bài thuốc hạ Lipoprotein máu sơn tra nhị trần đối với hệ thống tạo máu

Research objectives: 1. To detennine acute toxicity of the Son Tra Nhi Tran fonnular; 2. To evaluate the effects of the fonnular in general condition, weight and haematopoetic function of the rabbits, Subjects and Methods: 35 white mice (Swiss Musmusculus) used for evaluating the acute toxicity. The study was conducted follow the Lichfield Wilcoxon method. 20 Orytolagus Cunicilus rabbits used to study the hematopoietic function. It was divided into two groups: control group: taking water; study group: taking the medication with the dose of 3g/kg/day, both groups were taken continuously in 60 days. Results and conclusions: No acute toxicity (LD50) has been found; taking empirical fonnular Son Tra Nhi Tran within 60 days with dose of 3g/kg/day did not significantly influence the general condition, weight and haematopoetic function of the rabbits.