Objectives: Gastric ulcer is a chronis disease with a lot of dangerous complications and H. pylori is a major cause of gastric ulcer. Eradicating H. pylori helps reducing ulcer relapse and preventing cancer. The aim of study: to evaluate the rate of H. pylori infection in gastric ulcer and efficacy of quadruple therapy RACM for 5 days in patients with gastric ulcer with H. pylori positive. Materials and methods: Total 98 patients with gastric ulcer have been performed the endoscopy and CLO-Test, treated with quadruple therapy RACM for 5 days and evaluate efficacy 4 weeks after ending treatment. Results: The rate of H. pylori in gastric ulcer is 82.65 percent. The rate of H. pylori eradication is 88.71 percent. The effect of reducing pain of therapy is 90.32 percent; and the rate of reducing pain: 96.37 percent in successfully H. pylorieradicated group and in the other group 42.85 percent (p 0.05). The effect of healing ulcer 'of therapy is 77.41 percent; and the rate of healing gastric ulcer: 83.63 percent in successfully H. pylori-eradicated group and in the other group 28.57 percent (p 0.05). The adverse effects of therapy included tiredness: 11.29 percent, lose appetite: 8.06 percent and diarrhea: 6.45 percent. Conclutions: Quadruple therapy RACM for 5 days showed an effective, safe and simple regime for eradicating H. pylori and should be considered to apply as the first lines treatment for H. pylori.
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