Nghiên cứu tỷ lệ nhiễm HCV, xác định kiểu gen (genotype) của các chửng HCV ở bệnh nhân đến khám và điều trị tại Bệnh viện Bệnh nhiệt đới Trung ướng từ 6/2012 đến 6/2016

Hepatitis C is one of the dangerous diseases and is a matter of concern for public health by the number of people infected is increasing and may lead to severe consequences such as chronic hepatitis, cirrhosis and hepato-cellular carcinoma. The aim of this study was to identify the prevalence of HCV and describe genotypes of HCV strains in patients who were examined and treated in National Hospital for Tropical Diseases from 6/2012 to 6/2016. Subjects and Methods: All patients who were examined and treated at the National Hospital of Tropical Diseases is made immune tests, viral load and analyze HCV genotype perform by sequencing at NS5B from 6/2012 to 6/2016. Results: The prevalence of hepatitis C virus in the total number of patients examined and treated at the hospital was 4.04 percent. Prevalence of hepatitis C virus is account for 25.86 percent of the patients with hepatitis virus types. In total 612 patients being tested for sequencing is the highest proportion of genotype 6 (46.9 percent), followed by genotype 1 (40.7 percent), genotype 3 (6.4 percent) and lowest in genotype 2 (2 percent). Genotype 1 has 3 subtype 1a (19.6 percent), 1b (18.4 percent) and 1q (0.2 percent). Subtype 2a (1.9 percent), subtype 3a (2 percent), 3b (4.6 percent) while genotype 6 detected 8 subtypes which genotype 6a and 6e highest proportion 24.9 percent and 10.2 percent.