Nghiên cứu ứng dụng phác đồ Graall 2005 điều trị bạch cầu cấp dòng lympho người lớn pH (-): Theo dõi 3 năm

Objectives: To report the efficacy and safety of GRAALL 2005 protocol in the treatment of patients with Ph chromosome negative acute lymphocytic leukemia (Ph (-) ALL). Method and patients: Adult Ph(-) ALL patient was treated with GRAALL 2005 protocole at hospital since October 2009 to May 2012. Results: Among 16 patients on chemotherapy, their average age was 36 years, the total response rate 93 percent following induction chemotherapy and the median overall survival 25 + or - 3 months, disease free survival 23 + or - 3 months, induction death 6 percent. Conclusions: GRAALL 2005 protocol is associated with significantly improved survival rates.