Nhận xét sự thay đổi huyết động sau áp dụng liệu pháp điều trị sớm theo mục tiêu ở bệnh nhân sốc nhiễm khuẩn

Background: Septic shock is common in ICU and has high mortality. EGDT has been used early to help improve survival rate and red lice complication. This study was to evaluate the EGDT's effectiveness on hemodynamic and tissue perfusion improvement including pulse rate, mean arterial pressure MAP, CVP, Scv02 and plasma lactate. Method: There were 32 patients with septic shock enrolled and were resussitated with EGDT on the first 6 hours after admission. These patient were then divided into two groups: N1 success 22 pts (68,75 percent) and N2 failure 10 pts (31,25 percent). Results: In septic shock, there were significantly improvement in hemodynamic parameters and tissue perfusion index (p0,05) after the first 6 hours. There was significantly difference between N1 success group and N2 failure group about Scv02 and plasma lactate after implementing EGDT. Conclusions: EGDT hepls impove the hemodynamic parameter and tissue perfusion index in septic shock patients.