The size and number of gallbladder polyps are used to differentiate between benign and malignant lesions before surgery. Since 1987, laparoscopic cholecystectomy has been widely used as the management method of choice for gallbladder lesions. The results of a clinicopathologic study of polypoid lesions of the gallbladder that data from 232 patients with polypoid lesions of the gallbladder treated by laparoscopic cholecystectomy were reviewed retrospectively. Univariate analysis showed that malignancy in polypoid lesions of the gallbladder correlated significantly with age, size, and number of the lesions. Laparoscopic cholecystectomy is a safe and feasible method for gallbladder polypoid lesions. Neoplastic change in polypoid lesions of the gallbladder should be considered when a patient older than 50 years of age has a polypoid lesion larger than 10mm. Cancer should be suspected when a polypoid lesion of the gallbladder is larger than 15mm.
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