Objectives: To investigate the plasma lipid disorders and related factors in patients with primary gout. Patients: 127 men with primary gout and 127 healthy age-matched men examined in the department from 3/2012-3/2014 were included. Methods: cross-sectional study. Patients were underwent clinical examination and blood tests (basic tests, plasma lipid). Results: Mean age: 49.3 +/- 15.6; disease duration: 2.5 +/- 1.6 yrs. Prevalence of plasma lipid disorders were significantly higher (p 0.001) in gout patients for high total cholesterol (49.3 vs 47.8 percent)low HDL-Cholesterol (50.5 percent vs 26.1 percent), high total cholesterol (48.0 vs 33.9 percent), high LDL-C (51.2 vs 37.0 percent), low HDL-C (53.5 vs 22.8 percent) and high tang triglycerides (56.7 vs 32.3 percent), atherosclerotic index (total cholesterol/HDL-C (3.95 +/- 1.37 vs 3.45 +/- 1.83). Related factors to plasma lipid disorders were age, family history of cardiovascular diseases, smoking, drinking beer and alcohol, infrequent physical activities, obese, plasma uric acid and tophus nodule. Conclusions: Prevalence of plasma lipid disorders was rather higher in gout patierts, varied from 48.0 to 56.7 percent; these disorders were significantly related to smoking, drinking beer and alcohol, infrequent physical activities, obese, plasma uric acid and tophus nodule. Therefore, doctors should well control disease's activity and encourage patients to change life style in order to reduce plasma lipid disorders and cardiovascular risk factors in gqut patients.
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