So sánh kết quả sau đặt stent ống động mạch có và không phủ thuốc trên bệnh nhân tim bẩm sinh tuần hoàn phổi phụ thuộc ống động mạch tại Bệnh viện Nhi Đồng 2

There have been no clinical studies evaluating the use of drug-eluting stents (DES) versus bare metal stents (BMS) for infants who underwent ductus arteriosus stent placement for ductal-dependent pulmonary blood flow in VietNam. We aimed to compare the use of first-generation DES to BMS in infants who underwent ductus arteriosus stenting for duct dependent pulmonary circulation. Objective: the goal is to compare the outcome of infants who underwent ductus arteriosus stenting for ductal-dependent pulmonary blood flow f-rom January 2017 to April 2020 at Department of Cardiology in children Hospital # 2. Method: A retrospective study was performed on 102 patients (68 BMS and 34 DES) who met inclusion criteria. Results: At the time of ≥3 months after stent implantation, according to the NAKATA index, the figures for the DES and BMS group were 350.2 ± 201.4 mm2 /m2 and 289.8 ± 128.8 mm2 /m2 . As for the Mc Goon Index, the value were 1.9 ± 0.4 and 1.8 ± 0.3, respectively. Mortality rates in the DES and BMS group was 5.8% and 4.8%. The rates of stent blockage in the DES and BMS group was 0% and 1.5%. In the group receiving DES, 67.6% of the patients had stent stenosis in comparision to 70.5 % in the BMS group. Between 3 and 6 months after stent implantation. The rate of stent stenosis was 51.5% in BMS as opposed to 23.5% in DES group; p = 0.007. Conclusion: There were no statistically significant differences between those receiving DES and those receiving BMS in the composite outcome of death, stent blockage or stenosis after ≥ 3 months stenting. However, stent stenosis occurs earlier in in the BMS group than DES group during the period f-rom 3 to 6 months after ductus arteriosus stenting.