Nowadays allergy occupies an important place in modem medicine, the world 15 - 20 percent of the population are allergic, in which 20 percent of patients with airway allergen sensitization. By 2015 there may be up to half of the population have allergies. House dust allergens is one of the most common causes of the diseaseatopy, large proportion of allergic rhinitis. Allergic rhinitis treatment strategy depends on four basic principles is to avoid contact with allergens, drug treatment, specific immune therapy and educate patients. Specific immune has two main lines: Subcutaneous Immunotherapy (SCIT) and Sublingual Immunotherapy (SLIT). Subjects and methods: 120 patients were divided into two groups-specific immunotherapy injections and sublingual from 6/2010 - 6/2012, compared to the change in vitro tests. Results and discussion: comparison of in vitro tests on two groups patients VMDU by house dust allergens Dermatophagoides pteronyssinus, the author see two methods are remarkably effective and the same, the difference is not statistical significance (p 0.05).
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