Sự biểu lộ của C-met trong ung thư biểu mô tuyến dạ dày vùng hang vị

To evaluate the level of C-met expression and its relationship with the endoscopic and histopathological features of patients with gastric antral adenocarcinoma. Subjects and methods: The study was performed on 150 cases of gastric adenocarcinoma operated at Hanoi K Hospital from January 2018 to december 2019 by cross-sectional descriptive method. Results: C-met expression was found in 51.3% of gastric adenocarcinomas. Expression of C-met in infiltrates, polyps, ulcers and polypoid was 41.7%, 50%, 51.3% and 53.7% (p > 0.05). According to Lauren's histological classification, 56,9% of intestinal type tumors had C-met expression compared to 26.5% off diffused types and 85,7% of mixed types, respectively (p < 0.01). Accorrding to Expression of C-met was different in mixed 85.7% papillary 66.7%, mucinous 66.7%, tubular 54.5% and signet ring cell 26.5% types (p < 0.05). Expression of C-met in different grades: 48.3% of well-differentiated, 62.5% of moderately differentiated and 43.1% of poorly differentiated tumors (p > 0.05).