Tỉ lệ, đặc điểm, yếu tố nguy cơ và ảnh hưởng của tổn thương thận cấp ở bệnh nhân Covid-19 nặng và nguy kịch

This study aimed to describe the characteristics and to determine the incidence, risk factors and effects of acute kidney injury (AKI) in severe and critical COVID-19 patients. Method: We retrospectively studied COVID-19 patients admitted to the COVID-19 Intensive Care Center, University Medical Center Ho Chi Minh City. Results: The study recruited 356 severe and critical COVID-19 patients. The AKI incidence was 59.8%, among which stage 2 of 13.8% and stage 3 of 23.6%. Cytokine score and colistin use were independently related to the occurrence of AKI. The median time of hospital stay was of 15 days. 14.6%, 50.3%, and 17.42% of patients required renal replacement therapy, invasive mechanical ventilation, and blood transfusion, respectively. The overall mortality was 35.96%. The patients with AKI had a longer hospital stay, higher rate of invasive mechanical ventilation, blood transfusion, and mortality. Conclusions: AKI was common in severe and critical COVID-19 patients and associated with increased disease severity, prolonged hospital stay and higher mortality.