The purpose of this study was to examine the association between asthma severity and skin test reactivity to seven common indoor allergens. The charts of 150 asthmatic children, aged 2 to 15 years, seen in a allergy clinic of National Hospital of Pediatrics from Febrarury to July 2012 were reviewed to obtain the results of skin prick tests to common indoor allergens and asthma severity. Logistic regression for ordinal data was used to examine the association between skin test reactivity and asthma severity (mild, moderate or severe). Results: Children with minimum one positive skin prick test were 60,7 percent. The rate of allergen sensitivities were Dermatophagoides Pteronyssinus (67 percent), Dermatophagoides Farinae (65,9 percent), house dust or the acarine mite (59,3 percent), animal danders: dog (15,4 percent), cat (9,9 percent), coach road (6,6 percent), Aspergilluss (4,4 percent). Children with positive skin test were more likely to have a higher asthma severity rating than children with a negative skin test (OR=S,9), Children with positive skin test more to allergens were been higher asthma severity grate 2 and 3 than 1 (P 0.05). Children with asthma severity of grate 2 and 3 have higher skin test to D. Pteronyssinus, D. Farinae and dust mite allergens. Conclusion: Our data also suggest that sensitization to indoor allergens, expectly dust mite is a risk factor for more severe disease in these asthmatic children.
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