Tình hình sử dụng kháng sinh trên trẻ hen ở Bệnh viện Nhi Đồng 1

Respiratory tract infections are the most common reasons for asthma exacerbations. Because bacterial infections are associated with the progress of respiratory tract inflammation and severity of exacerbations, antibiotic therapy may decrease severity of exacerbation. Objective: To determine the rate of prescription of antibiotics, length of hospital stay, factors associated with length of hospital stay and prescription of antibiotics in asthma patients at the Children’s Hospital 1 f-rom December 2019 to June 2020. Methods: Cross – sectional study 216 asthmatic children admitted to the General Internal Department 2. Antibiotics were prescribed up to 80.1% of asthmatic children while only 44% of the cases had evidence of bacterial infection. Results: There were 216 asthmatic children admitted to the General Internal Department 2. Antibiotics were prescribed up to 80.1% of asthmatic children while only 44% of the cases had evidence of bacterial infection. Prescription of antibiotics was significantly more likely in younger asthmatic children (p <0.001), in patients who curently taken antibiotics (p <0.001; OR= 21.72; 95% CI: 5.30-189.08) and in cases of first-time asthma diagnosis (p=0.002; OR= 2.83; 95% CI: 1.35-5.94). The median length of stay was 4(3;6) days. Length of hospital stay showed significantly prolonged in younger asthmatic children (p=0.029), in patients with more severe exacerbations (p=0.033), in cases prescribed with antibiotics (p <0.001), in asthmatics using of antibiotics without evidence of bacterial infection (p <0.001), in patients who have accompanying other disorders (p <0.001).