Tình trạng kháng kháng sinh và một số gen kháng thuốc của Streptococcus suis gây bệnh trên người

Streptococcus suis (S. suis) is a human pathogen that causes a number of diseases and has the ability to spread epidemics with significant fatality rates, particularly in septic shock patients. Objectives: To analyze antibiotic resistance and the expression of drug resistance genes of S. suis in human. Methods: A prospective, observational study to analysis of the antibiotic resistance of S. suis by E-test technique and resistance genes of S. suis. Results: 90% of patients were male. S. suis strains were completely susceptible to penicillins, ampicillin, ceftriaxone, linezolid, and vancomycin. Antibiotics with a high rate of resistance were erythromycin (76.3%), clindamycin (73.5%), and tetracycline (97.6%). Antibiotic resistance genes included: ant(6), tet(B), tet(O), and erm(B) with prevalence of 78.75%, 75%, 28.75%, and 60%, respectively. Conclusion: S. suis has remained resistant to commonly used antibiotics such as penicillin, ampicillin, and ceftriaxone. There was an association of the frequency of resistance genes and antibiotic resistance on the antibiogram.