Gestational trophoblastic disease usually appears in patients with a history of abnormal pregnancy. Although the disease is malignancies but has good prognosis if being early detected and treated. Studying characteristics of patients will help diagnosis and effective treatment. Analysis of data on 568 patients with single MTX chemotherapy in 5 years time in central maternal hospital show that the common history of GTD is after pregnancy eggs (82.04 percent). Some popular symptoms, have high value in diagnostic and prognosis, such as persistent vaginal breeding (63.4 percent), uterus is larger than normal (63.6). The rate of metastasis in the single MTX chemotherapy group is low (9.6 percent), mainly lung metastases (67.27 percent), vagina (25.5 percent). BetahCG concentration at presentation in patients treated with MTX alone usually below 40.000 lU/L (79.9 percent). The majority of patients (76 percent) had a total score of prognostic factors under 7 points according to WHO 2006 criteria.
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