Đánh giá tương tác thuốc bất lợi trong đơn thuốc xuất viện và điều trị ngoại trú tại bệnh viện đa khoa hạng I

Drug interactions in prescriptions for 1502 outpatients and patients at hospital discharge in a community hospital were assessed by Micromedex Drug Interaction Checking software. The study revealed a relatively high prevalence of prescriptions committing drug interactions and even potential ones (17.8 percent and 2.9 percent, respectively). Erderly patients, and cardiovascular ones and the higher number of drugs/prescription were the common risk factors for drug interactions. Interactions resulting in kyperkalemia and digoxin toxicity were the two of most common potential and occurrence. Changes in medication at discharge resulted in other drug interactions, including potential ones. Efforts should be needed to minimize harms associated with drug interactions occurring at discharge and in outpatients.