Management of cirrhotic patients with ascites Is based on improving excretion of sodium with diuretics and dietary Na restriction. The Spot U Na/K ration may replace the the cumbersome 24 hr urine collection but only few data have been confirmed. Objective to evaluate the diagnostic value of spot U Na/K ratio 1 with 24hr UNa 78 mmol.day in cirrhotic patients with ascites. Patients and methods. 109 cirrhotic patients with ascites were' recruited in the study. 24 hr Una, and spot U Na/K ratio were measured and analyzed. Results. Mean of 24hr U Na was 143,8 + or - 95,6. 68,81 percent of 24hr urine specimens contained 78mmol of Na/day. 77,98 percent of speciments had Una/K ratio 1. When compared with 24hr Una 78mmol with spot Na/K urine 1, Se 90,67 percent, Sp 44,11 percent, PPV 78,165, NPV 68,18 percent., From the ROC curve, the best cut off point was U Na/K ration=3,1 (AUROC=0,78). The authors found that the sensitivity was and specificity was. Conclusions: The results suggest that U Na/K greater than 3,1 is an accurate, cost effective, and convenient method for repacing 24h U Na.
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