Objective: To evaluate results and give some comments over the cases large meningiomas were operated at Khanh Hoa General hospital. Material and methods: Retrospective study 6 cases large meningiomas was surgical treatment at a hospital in Khanh Hoa 2 years (2010-2012). Investigation of clinical signs when a patient is admitted. Using CT Scan and MRI with contrast enhancement in the diagnosis. .Tumor resection with microscope is the method of choice. The level of tumor resection assessed by Simpson's classification. All cases are made of anapathology. Patient's condition before and after surgery were evaluated based on functional living indexKarnofsky (KPS). Results: Age youngest 24 and the oldest 67. All cases are manifestations of a condition increases intracranial pressure and 4 cases are the presence of focal neurologic signs. Location of the tumor are located on the tent. The size of the tumor: three cases 5-6cm, over 6cm with a case and one cases is over 7cm diameter. The level of resection: Simpson I: 04, Simpson II: 01, Simpson IV: 01. Results anapathology: 5 cases are syncytial meningioma, and 1 cases is angioblastic meninggioma. Surgical time and blood for angioblastic meningioma are to differ compared to other types. Postoperative complications: 1 case with cerebral edema. After all surgical patients have improved on vital functions. Conclusion: For the large tumor volume the support of instruments such as microscope and hemostatic is essential to prevent damage to impotant brain structures, good hemostasis and tumor resection easier. In the future need to develop Digital Subtraction Angiography (DSA) before surgery to help evaluate tumor blood vessels. The closely before, during and after surgery between the neurosurgeon and anesthesia resuscitation is crucial to the success of this surgery.
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