Khả năng kích thích miễn dịch của Arabinoxylan tách chiết từ cám gạo Việt Nam

Arabinoxylan extracted from Vietnamese rice bran was examined for its effect on murine lymphocyte activity. The mice were administered orally at four different doses: 50, 75, 100, 200 mg/kg/day for 30 days. The highest secretion of INF-y in mouse serum was 340 pg/ml at 200 mgl kg/day dosage. However, the maxium increasing rate in mortality of Sarcoma 180 cell line was 1833 percent at a dose of 100 mg/kg/day, in comparison to the control. Thus, Arabinoxylan from Vietnamese rice bran acts as a potential immunomodulator to stimulate the immune system through stimulating the natural killer cell activity and secretion of INF-y.