Khảo sát phương pháp định lượng Cefaclor

Sustained release formulation is desirable for Cefaclor, as its half-life is very short. The current Vietnam pharmaceutical market has circulated no home-mad preparations of cefaclor in sustened release form, but foreign ones at high parices. This study was designed to investigate qualitative, quantitative determination of cefador in such dosage form by HPLC and UV-Vis spectrophotometry. The linearity, detection limit of HPLC methol and UV-Vis spectrophotometry were R2 = 0,99623 and 0,17-0,40 mg/ml; R2 = 0,9987 and 8,7545 ug/ml, respectivly. The formulation of sustained release cefaclor tablet is being examined.