Nghiên cứu kết quả điều trị ung thư vòm mũi họng bằng hóa xạ trị đồng thời tại Bệnh viện Trung ương Huế

Objective: the authors evaluated the benefits (responses and toxicities) of concurent chemoirradiation in treatement nasopharyngeal carcinoma (NPC). Materials and Methods: 41 patients (prospective) advanced NPC treated at Centre Oncology of Hue Central hospital, between January, 2013 and September, 2014. NPC were treated with by CRT using Cisplatin 30mglm21weekly in 6 weeks, total irradiation dose, (70 Gy, tumor; 50 Gy, nodes). Results: Characteristic: median age 46.41 (range 7-68); male/female 2; palpapble cervical lymh nodes 82.9 percent. VCNT (90.2 percent). Stage III (51.2 percent) and IV (41.5 percent); Complete rate is 85.3 percent; partial response rate 14. 7 percent. Acute toxicities of CRT were as follows: leukopenia (51.2 percent), anemia (14.6 percent). No patient developed moderate to severe mucositis and xerostomia ( or = Grade 3). Conclusions: concurent chemoirradiation is a method to improve locoregional, region node control and increase response rate, however also increasing acute toxicities, but low level and acceptable.