Nghiên cứu thăm dò điện sinh lý bệnh thần kinh ngoại vi ở người đái tháo đường Typ 2

Electrophysiological examinations play a importtant role in the diagnosis and prognosis of the diabetic polyneuropathy, especially in diabetes type 2. Objective: To investigate the electrophysiological feature of the polyneuropathy in type 2 diabetes glycemic control (DGC) and glycemic non-control (DGNC) groups. Methods: Electrophysiological examinations were performed in 38 patients of DGC and 42 patients of DGNC group with cross-sectional description and comparison of electrophysiological parameters of diabetic polyneuropathy between groups. Results: Reduction of the amplitude and of the nerve conduction studies are seen in both groups. These rate were major in the tibial nerve, common peroneal nerve, median and ulnar nerve. Abnormal Hoffmann reflexes, reduction of the amplitude and of the nerve conduction studies on the tibial nerve, common peroneal nerve in DGNC group were significantly higher compared to DGC group. Conclusion: Electrophysiological polyneuropathy in the patients with diabetes type 2 is demyelinating and axonal as a distal symmetrical process with greater lower-limb than upper-limb involvement. Majority of the electrophysiological parameters in the DGNC group is higher than in the DGC group and good control of glycemia significantly reduce the polyneuropathy in diabetes-type 2 patients.