Nghiên cứu tình trạng đề kháng kháng sinh và tỷ lệ mang gen mecA của các chủng Staphylococcus Aureus ở bệnh nhân nhiễm khuẩn huyết tại Bệnh viện Bệnh nhiệt đới Trung ương và Bệnh viện Quân y 103

Objectives: Determine the rate of antibiotic resistance and ratio of the mecA gene of S. aureus isolated from septicemia patients. Subjects: 43 S. aureus strains were isolated from septicemia patients in NHTD and Military Hospital No.103 during period of December, 2012 to June, 2014. Methods: Cross - sectional descriptive study (see again). Results and conclusions: Level of antibiotic resistance: 53.49 percent MRSA strains; the highest resistance was to penicillin, accounting for 100 percent, followed by erythromycin (65.12 percent) and clindamycin 60.47 percent. quinolone group was highly sensitive: ciprofloxacin 83.72 percent; levofloxacin 86.05 percent and moxifloxacin 86.05 percent. Some antibiotics were completely sensitive (100 percent), include: Vancomycin, tigecycline, linezolid, quinupristinjdalfopristin. By comparison of the antibiotic resistance between MRSA and MSSA group shown that: the rate resistance of MRSA group to clindamycin, erythromycin, tetracycline, levofloxacin, ciprofloxacin, moxifloxacin was higher than MSSA group, with p 0.05. In addition, there were 25 Staphylococcus aureus strains (58.14 percent) possessed mecA gene; and 22 of 23 MRSA strains (95.65 percent) showed to be having mecA gene; only 15 percent strains in MSSA group also possessed this gene.