Background: Psoriasis is a chronic inflammatory dermatosis which affects more than 2 percent .of the population. This disease may be associated with an increased morbidity and mortality from cardiovascular events, metabolic syndrome, serum lipid abnormalities, etc. This study takes part in evaluating the lipid profiles in patients with psoriasis in Dermatology hospital in HCM city, which helps to diagnosis and treat hyperlipidaemia early in patients with psoriasis to prevent the atherosclerosis. Objective: To compare the lipid profiles in psoriatic patients with non-affected individuals, to find correlation with risk factors, induration and severity. Method: Performing a analyzed cross-sectional study in 50 psoriatic patients and 50 healthy people. Results: The serum triglyceride was significantly higher (p =0.02), and serum HDL was significantly lower in patients with psoriasis (p = 0.001, respectively). The serum cholesterol and LDL of psoriatic patients were not significantly different from those of healthy people. There were no significant correlation between the lipid profiles and risk factors, and induration in psoriatic patients. The correlation between LDL and PASI were significant (p = 0.02). Conclusion: It is necessary to do creening and treatment of hyperlipidaemia early in patients with psoriasis to prevent the atherosclerosis and its complications.
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