Đánh giá chức năng thất trái của bệnh nhân trước và sau cấy máy tái đồng bộ cơ tim (CRT) bằng phương pháp siêu âm tim đánh dấu mô ở bệnh nhân suy tim nặng

We aimed to evaluate the left ventricular function before and after implantation of cardiac resynchronization therapy (CRT) device by using tissue Doppler echocardiography. Methods: A prospective longitudinal follow-up in 33 patients with severe heart failure (left ventricular ejection fraction ≤ 35%) and QRS duration ≥ 120 ms, who underwent a CRT device implantation in Vietnam National Heart Institute - Bach Mai Hospital. Results: The mean age was 60 years old and the proportion of males was 84,8 %. The pre-implantation baseline QRS duration was 133.9 ms. At the time of discharge, 1 month and 3 months follow-up after implantation, the QRS duration was 124.4 ms; 115.6 ms; 111.8 ms, respectively. The severity of mitral regurgitation was improved and the systolic pulmonary artery pressure was decreased significantly after CRT implantation and during follow-up (p<0.05). The diastolic left ventricular function improved significantly from 1 month follow-up after CRT implantation with a decrease in the E/e' index, and e', a' and s' indices were increased (p<0.05). The left ventricular global longitudinal strain was improved significantly from 1 month follow-up after CRT implantation. Conclusions: Patients, who underwent CRT implantation, had a reduction of the QRS duration from 133.9 ms to 111.8 ms after 3 months follow-up. The severity of mitral regurgitation was decreased, and the pulmonary artery systolic pressure was decreased after CRT implantation. The diastolic left ventricular function and the left ventricular global longitudinal strain were improved significantly from 1 month follow-up after CRT implantation.