Giá trị của đặt clip đánh dấu trong sinh thiết kim lõi dưới sự hướng dẫn của siêu âm đối với việc định vị ung thư vú trước và sau khi hóa trị tân bổ trợ

The placement of intramammary marker clips has proven to be helpful for tumor localization in patients undergoing neoadjuvant chemotherapy and breast-conserving surgery. The study was to investigate the feasibility of using a clip marker system for breast cancer localization and its influence on the imaging assessment of treatment responses after neoadjuvant chemotherapy. Indication: Patients with a suspicion of invasive breast cancer with diameters of at least 2 cm (cT2), underwent preoperative sonographically guided core needle biopsy using a single-use breast biopsy system and intramammary clip marking using a directly adapted clip system based on the established Marker™, before their scheduled preoperative neoadjuvant chemotherapy. Localization of the intramammary marker clip was controlled by Ultrasound and digital breast tomosynthesis. Evaluation: Ultrasound and mammography help assess clip location. It also helps assess the clinical response to neo-adjuvant chemotherapy. No complications related to clipping were noted and there were no difficulties in assessing treatment response to neoadjuvant chemotherapy. Conclusion: The study underscores the importance of intramammary marking clip systems before neoadjuvant chemotherapy. Placement of marker clips is advised to facilitate accurate tumor bed localization. It helps the surgeon know the position of the cancer bed in breast-conserving surgery. In addition, it also helps the pathologist to accurately assess whether the histopathological response is complete or not.