Kết cục của thông liên thất đơn thuần trên thai nhi được chẩn đoán trước sinh tại Bệnh viện Từ Dũ

Ventricular septal defect (VSD) is a common heart birth defect. VSD is frequently isolated; however, it can occur in association with other congenital heart defects. Early dection of VSD is tremendously improved with technical advances in diagnostic imaging technology. Isolated ventricular septal defect, which may self-limit or require intervention after birth, is important in antenatal care strategy and postpartum follow-up. Objectives: To describe the outcome of the fetus having VSD was diagnosted in Tu Du hospital and the rate of chromosomal anomalies in such cases. Methods: A case series was conducted on the pregnant women, who had the fetus with confirmed of VSD at 18-24 weeks of gestation, had pregnancy care at Prenatal Care Unit, Tu Du hospital f-rom 31/12/2019 forward. The c-haracteristics of pregnancies and VSD were analyzed, including follow-up until 6 months of age. Results: Out of 46 cases of VSD included in the study, muscular VSD was 43.47%, perimembranous VSD was 41.30%, the outlet VSD was 13.06%, the inlet VSD was 2.17% and mean size of the opening was 2.06 ± 1.95mm. There was no chromosomal abnormality in 20 cases of chromosomal analysis. Gestational age at birth range was 38.13±2.13 weeks (82.61% ≥ 37 weeks), weight at birth range was 2827.17±624.3gr (82.61% ≥ 2500gr). Apgar ≥ 7 points: 1 minute 82.61%, 5 minutes 97.8%. The rate of Neonatal Special Care admission was 8.7%. Non of live-born needs heart intervention during 6 months postpartum with the number of spontaneous closures in 20 of the 44 infants (45.45%). Conclusions: Isolated VSD diagnosed prenatally does not appear to have chromosomal abnormalites and has a favorable clinical outcome follow-up until 6 months of age. But the genetic analysis should be recommended.