Kết quả điều trị bước đầu 02 ca lâm sàng u nguyên bào thần kinh khứu giác tại bệnh viện K

This study aimed at describing clinical, subclinical characteristics, and the initial result of treatment on two cases of olfactory neuroblastoma by surgical treatment combined with chemotherapy and radiotherapy at the National Cancer Hospital. Subjects and methods: The cross-sectional study and reporting a cluster of cases was conducted on two patients with a convenient sampling method. The period is from October 2020 to October 2021. Results: The sexes of the two patients were male, with ages 44 and 50 respectively. The main clinical symptoms of the patients were stuffy nose, one-sided nasal bleeding, migraine headache. The subclinical test results were consistent with the medical literature describing the disease. Applying surgical treatment method combining chemotherapy and radiation therapy at the same time after surgery, with a dose of 60Gy/30fx and chemical Cisplatin 100mg/m2 for a 3-week multi-cycle. Treatment results showed that two patients responded completely and had no complications on the hematopoietic system. Conclusion: The surgical treatment combined with chemotherapy and radiotherapy at the same time after surgery initially has a good effect on these patients.