Nghiên cứu căn nguyên và tính kháng kháng sinh của một số vi khuẩn ở bệnh nhân nhiễm khuẩn huyết điều trị tại Bệnh viện đa khoa Trung ướng Huế 2011-2015

Background: Sepsis is one of the most important infections. Antibiotic resistance has a big influence to treatment's outcome. Subjects and method: Patients diagnosed as sepsis treated at Hue Central hospital, since Jan. 2011 to December 2015. Retrospective study Results: Gastrointestinal and hepatobiliary tracts are the most common source (24.9 percent and 14.8 percent), then respiratory infections (12.2 percent). The most isolated agents are E. coli (47.6 percent), S. suis (23.8 percent) and K. pneumoniae (5.8 percent). E. coli, K. pneumoniae caused the high rate of septic shock. The highest rate of mortality found in group of P. aeruginosa, A. baumannii and S. pneumoniae (100.0 percent). Then E. coli (63.6 percent), K. pneumoniae(46.7 percent) and S. suis (50.0 percent). Over 30 percent of isolated E. coli resistant to ampicillin, ceftriaxon and ciprofloxacin. Most of them still sensitive to imipenem, meropenem and amikacin. Streptococcus suis II sensitive to ceftriaxone, ampicillin, ofloxacin, levofloxacin, carbapenem. Acinetobacter beumannii resistant to cephalosporin, fluoroquinolon, carbapenem, aminoglycosid; only sensitive to colistin. Conclusions: The most isolated agents are E. coli, K. pneumoniae and S. suis. E. coli, K. pneumoniae caused the high rate of septic shock. The highest rate of mortality found in group of P. aeruginosa, A. baumannii and S. pneumoniae. Antibiotic resistance of E. coli, A. baumannii, K. pneumoniae are increasing.