Nghiên cứu mật độ xương và tình trạng loãng xương ở bệnh nhân suy thận mãn tính

Osteoporosis is a common disease of the patients suffering from chronic renal failure related to disorders of mineral metabolism contributing to increase mortality rate due to renal failure. Objective: To study bone density and osteoporosis in chronic sufferers from renal failure. Subjects and research methods: 138 patients of chronic renal failure, including 67 males and 60 females, mean age 54.7, (19-78) years old, divided into two groups: sufferers from chronic renal failure not on dialysis consisting of 76 patients (levell, II, IIIa.); patients suffering from chronic renal hemodialysis (glade IIIb,IV and 109 people for testifying who do not have kidney disease. The ages and gender of these groups are the same. Methods: The prospective study is cross-sectional case-control comparison. The patients were measured with bone mineral density by DEXA method in the position of the lumbar spine and femoral neck. Statistical data were processed on SPSS 15.0 software. Conclusion: Femoral neck bone density of the group suffering from chronic renal failure compared with the controls, especially the windings move femoral neck and total femur (p 0.05 and p 0.01), significantly reduced. The group suffering from renal dialysis had density of decreased bone mainly in the femoral neck, joint bottom position move the thigh bone and femoral neck compared with the sufferers who do not have full dialysis (p 0.05). The density of the lumbar spine bone area between these groups is not clearly different for statistical significance. There is a higher proportion of osteoporosis and femoral neck between two groups: the sufferers from kidney failure and the controls. (69.75 percent against 40.36 percent, p 0.001). Similarly, the percentage increases higher in the patients suffering from renal dialysis than those who do not have hemodialysis (82.2 percent compared to 48.7 percent, p 0.001). The rate of the sparse and osteoporosis of the lumbar spine between these groups is not different for statistical significance (p 0.05).