Nghiên cứu sự thay đổi một số hormon và mức độ biểu hiện gen Kiss liên quan đến sự phát triển thể chất của học sinh nữ lứa tuổi dậy thì

The target of study is define the appearance levels of Kiss gene, define concentration and connection of some hormones to development of the physical of puberty girls. Method of study: Cross-sectional descriptive study. 68 students from the 6 grade to the 9 grade (from 12-16 years old) in urban school in Thai Nguyen city. Object study include: 2 groups: group 1 include female students in urban school in Thai Nguyen city who have no menstruation (31 students). Group 2 include female students of the rural secondary schools in Thai Nguyen who have menstruation (37 students). The index of study include: height, weight, menstrual status, the concentration of hormones: GH, T3, FT4, estradiol in serum and the appearance levels of Kiss gene. Result: - The concentration of GH and T3 hormones of female students in prepuberty (not menstrual) is higher than female students in puberty (with menstruation), with p 0.05 to 0.001. - The concentration of estradiol in the female students with menstruation higher than female students whithout menstruation, p 0.001. - The concentrations estradiol is positive correlation with height (r