Nguy kịch hô hấp cấp

Refractory severe hypoxemia is a cause of mortality in patients with ARDS. Pulmonary protective ventilation combined with prone-positioning improve oxygenation and reduce mortality in ARDS. Objectives Identify characteristics of the patient’s oxygenation progression and respiratory mechanics before, during, and after prone-positioning mechanical ventilation. Methods A case series study of ARDS patients was conducted at the Emergency Department and Intensive Care Department of Children's Hospital 2 from April 2019 to August 2020. Results There were 18 ARDS patients due to pneumonia treated with prone positioning ventilation. The percentage of patients with underlying diseases was 77.8%, 83.3% of patients with early onset of ARDS < 4 days, and 100% bilateral diffuse lung lesions on chest radiograph. The percentage of patients responding to prone positioning ventilation was 77.8%. The PaO2/FiO2, oxygen index (OI), values Ppeak and driving pressure were statistically improved at the post-prone positioning times when compared to before (p <0.05). Conclusion Our report showed that mechanical ventilation with prone position helped to improve blood oxygenation and respiratory mechanics in patients with moderate or severe ARDS.