So sánh kết quả điều trị Terlipressin và Octreotide kết hợp thắt vòng cao su trên bệnh nhân xơ gan có xuất huyết tiêu hóa do vỡ giãn tĩnh mạch thực quản

Comparison of treatment results of Terlipressin and Octreotide combined with rubber band ligation in cirrhotic patients with gastrointestinal bleeding due to ruptured esophageal varices at Can Tho Central General Hospital and Can Tho General Hospital. Materials and methods: Cross-sectional study with randomized intervention in cirrhotic patients with gastrointestinal bleeding due to ruptured esophageal varices from September 2022 to March 2024. Results: The number of blood transfusions in cirrhotic patients with gastrointestinal bleeding due to ruptured esophageal varices treated with drugs combined with rubber band ligation in the Telipressin group was 3.11 units less than in the Octreotide group position with 95% confidence interval ((-3.99 to -2.23), p < 0.01). Similarly, the group of patients treated with Terlipressin had a shorter hospital stay than the group of patients treated with Octreotide by 1.8 days with a 95% confidence interval ((-2.78 to -0.87), p = 0.002). The difference in mortality between the two groups of patients was not statistically significant. Conclusion: Terlipressin showed better treatment results than Octreotide in reducing the number of blood transfusions and number of hospital days. The mortality rate in both groups did not differ.