Tỷ lệ toan chuyển hoá trong tuần đầu sau sinh ở trẻ non tháng có cân nặng lúc sinh dưới 1500gr

Metabolic acidosis in the first week of life, one of the most common problems in preterm infants with birth weight less than 1500g, may be associated with morbidity, mortality, as well as poor growth, and neurodevelopmental impairment. This study was undertaken to determine the rate of metabolic acidosis on admission, during the first week of life, or recurrence and the mean time of recurrent metabolic acidosis in preterm infants with birth weight of less than 1500g. Methods This prospective case-series study involved 61 preterm infants, under 7 days old, with a birth weight less than 1500g, admitted to the NICU, Children's Hospital 2, from June 1, 2020, to October 31, 2020, had a blood gas. The metabolic acidosis and related variables were collected. Results The rate of acidosis was 80.3% on admission, was 98.4% in the first week and was 27.9% of recurrent acidosis, and the mean time of recurrent metabolic acidosis was 32.5 hours. Increased anion gap accounted for 91.5% of metabolic acidosis. Conclusions These data showed that metabolic acidosis is common during the first week of life in preterm infants with birth weight of less than 1500 g in the NICU. Most cases were increased anion gap metabolic acidosis