Laser assisted hatching - LAH began to be implemented in Vietnam in 2009. Currently, no study has evaluated the effectiveness of this technique on embryos of womens or = 38 years of age. Objective: To assess the effectiveness of LAH on embryos of womens or = 38 years of age. Study design: prospective, intervention. Subjects: 130 embryo transfer cycles of womens or = 38 years old were allocated into two groups: group 1: 58 cycles without LAH; group 2: 72 cycles with LAH before embryo transfer. Results: The pregnancy rate (PR) of group 1 lower than group 2 (no statistically significant): 17.14 percent and 22.22 percent (p = 0.2); implantation rate (IR) of group 1 lower than group 2 (no statistically significant, p = 0.84). Conclusion: LAH did not improve the pregnancy rate in IVF womens or = 38 years of age.
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