Đánh giá hiệu quả hóa chất phác đồ Irrinotecan kết hợp Cisplatin trong điều trị ung thư phổi tế bào nhỏ giai đoạn lan tràn

Objects: assessing the effects of Irrinotecan plus Osplatin regimen in the treatment of extensive stage small cell lung cancer. Subjects and methods: 47 patients with extensive stage small cell lung cancer were treated by Irrinotecan plus Cisplatin regimen. To evaluated symptom Improvement, response rate and toxicities. Results and conclusions: 83 percent of the patients achived symptom improvement, complete respon rate were 40.4 percent, neutropenia grade 3,4 were 23.4 percent, diarrhea grade 3.4 were 24.3 percent, vomiting and nausea were 36.1 percent.