Objective: Assessing the outcomes of the ablation of residual thyroid for the differentiated thyroid carcinoma patients after total thyroidectomy. Methods: 520 differentiated thyroid carcinoma patients after total thyroidectomy are administrated radioiodine with different doses of 30mCI, 50mCI and 100mCI at the Nuclear Medicine and Oncology Center of Bach Mai Hospital. Result: Before radioiodine administration the remnant thyroid tissues are 3.43 + or - 2.26g; 1-131 thyroid uptakes are 5.71 + or - 4.81 percent, serum thyroglobulin (Tg) concentrations are 146.37 + or - 71.930 mg/ml, serum TSH concentration are 56.44 + or - 21.56 UI/ml. After 6 months of radioiodine therapy, the rate of total ablation with the dose of 30mCI is 33.3 percent, with the dose of 50mCI is 60.1 percent and with the dose of 100mCI is 79.2 percent. In the patients with partial ablation, the volumes of remnant thyroid tissues, the 1-131 thyroid uptakes as well as serum thyroglobulin concentrations are reduced in comparison with the ones before radioiodine administration. Conclusion: Radioiodine therapy is the most effective and safe modality for the differentiated thyroid carcinoma.
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