Gây mê tĩnh mạch bằng propofol có kiểm soát nồng độ đích so với phương pháp chỉnh liều thông thường trong phẫu thuật bỏng

Research was carried out on 60 intravenous anesthesia patients randomly divided into 2 groups with 30 patients in each one in Anesthesiology in National Institute of Burns from January, 2012 to January, 2013. Group I was site effect controlled target concentration propofol intravenous anesthesia group and group II was manually adjusted propofol intravenous anesthesia group. The authors found: 1. The average propofol dose (mg/kg) for induction in the group I was lower than the group 1/ (1.83 mg/kg vs. 2 mg/kg), but induction duration in the group I was longer than the group 1/ (91.50s vs. 76.43s), so hemodynamic and respiratory parameters in the group I were more stable and adjusted more easily than the group II. Both groups maintained the anesthesia depth s 1 on the OAA/S score. However, anesthesia quality and the stability of patients in the group I were better than the group II, expressed on PRST score (1.65 in the group I and 2.73 in the group II. The dose adjustment times in the group I was fewer than the group II (0.80 times/h vs. 1.76 times/h). The recovery time of patients in the group I was longer than the group II (17.27 minutes vs. 15.90 minutes). 2. The unwanted effects were within limit, pulses and non invasive blood pressure in the group I less changed than in the group II and the anesthesia depth in the group I was more stable than in group II, the movements in surgery in the group I was fewer than in group II. The authors didn't see the severe side effects in anesthesia in both groups (cardiac affest, respiratory failure...).